By P. Cohen, S. Van Heyningen
Molecular motion of poisons and Viruses investigates the molecular motion of bacterial pollutants and viruses and its outstanding similarity to the mechanisms wherein many neural and hormonal stimuli regulate common mobile features. subject matters coated comprise the organic job of diphteria toxin; the position of cholera toxin within the legislation of hormone-sensitive adenylate cyclase; poisonous lectins and comparable proteins; and bacterial cytolysins (membrane-damaging toxins). constituted of 9 chapters, this quantity starts with a dialogue at the biosynthesis and organic job of diphtheria toxin, toxin-resistant mutant cells, and the access of toxin into cells and fragment A within the cytoplasm of residing cells. The reader is then systematically brought to using cholera toxin as a probe to review the legislation and interplay of adenylate cyclase parts; the poisonous motion of lectins and comparable proteins akin to abrin, ricin, and modeccin; and the power of bacterial cytolysins to wreck mobilephone membranes. the remainder chapters specialise in the mechanism of motion of colicin E2, colicin E3, and cloacin DF13; similarities within the motion of other bacterial pollution; the function of phone membranes in an infection with bacterial viruses and colicins; and the existence cycle and an infection mechanisms of bacteriophage T4. The ebook concludes with an research of the involvement of protein kinases in viral transformation. This monograph may be of curiosity to scholars, practitioners, and researchers in fields starting from molecular biology and biochemistry to telephone biology, bacteriology, and body structure.
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Molecular Action of Toxins and Viruses by P. Cohen, S. Van Heyningen