Download e-book for kindle: Life Science Automation Fundamentals and Applications by Mingjun Zhang, Bradley Nelson, Robin Felder

By Mingjun Zhang, Bradley Nelson, Robin Felder

ISBN-10: 1596931051

ISBN-13: 9781596931053

ISBN-10: 159693106X

ISBN-13: 9781596931060

Automation is facilitating really good breakthroughs in every thing from healthcare, pharmacology, and biotechnology to nanotechnology and genomics. Automation builders, scientists, and technicians desire an more and more refined knowing of either the organic sciences and the engineering concerned, and this finished source is the 1st interdisciplinary paintings that actually promises. After a superior grounding in lifestyles technology and automation engineering necessities, this critical source describes cutting-edge ideas for the layout and improvement of sensors and actuators, lab-on-a-chip and bio-MEMs structures, DNA and protein microarray fabrication automation, and drug supply automation. It then demonstrates how those instruments may be effectively built-in in larger-scale scale automation platforms in parts like bio-instrumentation, phone and tissue manipulation, and laboratory automation.

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Due to its relatively negative charge, DNA will move toward the positive node. Over time, fragments of DNA will travel a certain distance that is proportional to both size and charge; thus, variably sized pieces of DNA can be separated from each other and visualized. 8 A sample set of primers for each of the strands. 14 Introduction to Nucleic Acids and Clinical Laboratory Testing This process is affected by the chemical composition of the gel matrix. The gel matrix is a cross-linked web of molecules through which the aqueous solution and DNA can travel.

In particular, however, capillary electrophoresis can be used together with HPLC with regard to the information content of the results. In the past few years, capillary electrophoresis has developed into a powerful technique due to its high separation efficiency, short analysis times, and low sample and electrolyte consumption. The various application areas in research and diagnostics include the determination of peptides and proteins, nucleic acids, and pharmaceutical and agrochemical products.

Ligases (synthases) catalyze production of chemical bonds by connecting together two substrates using ATP. According to the type of substrate or the particular catalyst reaction concerned, the main groups are further divided into subgroups and sub-subgroups containing the individual enzymes. On the other hand, the specificity of an enzyme can be set towards certain compounds. For example, urease only catalyzes hydrolysis in urea. 1 Enzyme Kinetics Enzymes function as catalysts. With an enzyme present, the activation energy of a reaction is decreased, and the reaction takes place several times more rapidly than the same reaction without a catalyst [1, 13, 18].

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Life Science Automation Fundamentals and Applications (Bioinformatics & Biomedical Imaging) by Mingjun Zhang, Bradley Nelson, Robin Felder

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