By A. E. Baue (auth.), Priv.-Doz. Dr. med. Eugen Faist, Jonathan L. Meakins M.D., D.Sc., Prof. Dr. Friedrich W. Schildberg (eds.)
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Additional resources for Host Defense Dysfunction in Trauma, Shock and Sepsis: Mechanisms and Therapeutic Approaches
Arch Surg 120:1109-1115 12. Baue AE (1990) Theories and common threads in multiple organ failure. In: Baue AE (ed) Multiple organ failure: patient care and prevention. Mosby, St Louis, pp 473-486 13. Baker CE, Degutis LC (1986) Predicting outcome in multiple trauma patients. Infect Surg 5:243-245 14. Ziegler EJ et al. (1991) Treatment of gram-negative bacteremia and septic shock with HA-IA human monoclonal antibody against endotoxin. N Engl J Med 324:429-436 14 A. E. Baue: Progress in Trauma Care Through Understanding of Cell Biology of Injury 15.
The surgeon can, by preoperative care, give his patient the best chance to resist infection by improving host variables and diminishing potential bacterial contamination. In the operating room, bacteria can be controlled; the operation perfectly performed leaves a wound best able to resist infection. For example, a patient with 12 h of fecal peritonitis should not have the wound closed primarily. Infection rates are 50%-70% and entail important sequelae. Cruse  and Olson et al.  have shown that keeping individual surgeons informed of their wound infection rates keeps them low.
29]. One positive feature of this study was that the enteral feedings prevented upper gastrointestinal bleeding and eliminated the need for antacids of H 2 -blockers. Whether these patients benefited further from this approach could not be determined. Enteral nutrition was compared with parental nutrition in patients following major abdominal trauma by Moore et al.  They found that enteral nutrition was well tolerated in these severely injured patients and that the incidence of septic complications seemed to be reduced.
Host Defense Dysfunction in Trauma, Shock and Sepsis: Mechanisms and Therapeutic Approaches by A. E. Baue (auth.), Priv.-Doz. Dr. med. Eugen Faist, Jonathan L. Meakins M.D., D.Sc., Prof. Dr. Friedrich W. Schildberg (eds.)