New PDF release: Gene and Protein Evolution

By Jean-nicolas Volff

ISBN-10: 3805583400

ISBN-13: 9783805583404

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FEMS Yeast Res 2001;1:9–13. Tsai MJ, O’Malley BW: Molecular mechanisms of action of steroid/thyroid receptor superfamily members. Annu Rev Biochem 1994;63:451–486. Rain JC, Selig L, De Reuse H, Battaglia V, Reverdy C, et al: The protein-protein interaction map of Helicobacter pylori. Nature 2001;409:211–215. Butland G, Peregrin-Alvarez JM, Li J, Yang W, Yang X, et al: Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 2005;433:531–537. LaCount DJ, Vignali M, Chettier R, Phansalkar A, Bell R, et al: A protein interaction network of the malaria parasite Plasmodium falciparum.

Note that, despite having the same name, bacterial flagella are distinct in form, function and evolution from both archaeal and eukaryotic flagella. • biosynthesis of a molecular syringe that mediates the movement of bacterial ‘effector proteins’ into eukaryotic cells (a process known as ‘translocation’; mediated by non-flagellar T3SSs) [1, 2, 6]. Effector proteins subvert host cell biology to the bacterium’s advantage. In both cases, the ATPase-powered secretion system is woven into a larger apparatus that includes a hollow filamentous organelle – in the case of the flagellum, the flagellar hook and filament; in case of non-flagellar systems, the needle and the translocation apparatus.

The result indicates that the weaker relationship among PPI partners of proteins is, the more slowly the interacting proteins evolve. These results strongly suggested that the evolutionary features of the interacting proteins have been influenced by the type of their PPIs such as functional and framework modules. We clearly pointed out the advantage of utilizing a vast amount of information about PPIs in the molecular evolutionary studies of biological networks. In particular, we successfully showed that the evolution of proteins as the components of PPI networks can be understood, to a reasonably great extent, through the evolutionary rates.

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Gene and Protein Evolution by Jean-nicolas Volff

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