New PDF release: Computational Biology and Applied Bioinformatics

By Heitor Silverio Lopes - Leonardo Magalhães Cruz (Eds)

ISBN-10: 9533076291

ISBN-13: 9789533076294

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Biochemical experiments performed in parallel showed that this conserved arginine plays a role in the signal transduction process that involves ATP hydrolysis by DnaC that then leads to the release of DnaC from DnaB. Finally, the interaction of primase with DnaB that is coupled with primer formation is also apparently necessary for DnaC to dissociate from DnaB. 6. Conclusions In summary, the combination of various experimental approaches on the study of DnaC have led to insightful experiments that expand our understanding of the role of ATP binding and its hydrolysis by DnaC during the initiation of DNA replication.

Wanner and H. Mori (2006). Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection. Mol Syst Biol 2: 1-11 Beyer, A. (1997). Sequence analysis of the AAA protein family. Protein Sci 6(10): 2043-58, 0961-8368 (Print), 0961-8368 (Linking) Biswas, S. B. and E. E. Biswas-Fiss (2006). Quantitative analysis of binding of single-stranded DNA by Escherichia coli DnaB helicase and the DnaB-DnaC complex.

Cavalli-Sforza, L. & Edwards, A. (1967) Phylogenetic analysis. Models and estimation procedures. American Journal of Human Genetics 19(3 Pt 1):233. ; Garrity, G. & others. (2009) The Ribosomal Database Project: improved alignments and new tools for rRNA analysis. Nucleic Acids Research 37(suppl 1):D141-D145. ; Fagot, G. & Fertil, B. (1999) Genomic signature: characterization and classification of species assessed by chaos game representation of sequences. Mol Biol Evol 16(10):1391-9. (2004). MUSCLE: a multiple sequence alignment method with reduced time and space complexity.

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Computational Biology and Applied Bioinformatics by Heitor Silverio Lopes - Leonardo Magalhães Cruz (Eds)


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