By Prof. Dr. Wolfgang Leistenschneider, Prof. Dr. Reinhard Nagel (auth.)
Diagnostic and exfoliative cytology has this day completed a standing that few can have envisaged two decades in the past. whereas exfoliative cytology has lengthy been hired in gynecological prognosis, new and profitable spheres have now constructed within which cytological analysis performs a tremendous position. Exfoliative cytology, for instance, is greatly hired as an reduction within the non-stop evaluate of urinary tract tumors, and aspiration cytology within the prognosis of thyroid dis eases. This has given upward thrust to a growing to be call for for pathologists skilled in cytological prognosis. despite the fact that, clinicians with an curiosity in morphology have been frequently the 1st to undertake those easy and secure equipment, being certainly attracted through the opportunity to prevent carrying out biopsy, which, within the final research, is not anything under a surgical treatment. during this Atlas of Prostatic Cytology Leistenschneider and Nagel expertly show what should be completed whilst clinicians expert in morphology take an curiosity in cytological tools. not just have they got direct touch with the sufferer, yet additionally they benefit from instantly being able to investigate the result of their diagnostic tactics by means of interpreting the specimen acquired. From the technical viewpoint aspiration biopsy of the prostate is not at all an easy method and the problems concerned would appear to were underestimated within the preliminary part of enthusiastic acclaim. therefore it's been commonplace for clinicians and pathologists to be disenchanted via the excessive fee of unsatisfactory samples got through this method.
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Additional info for Atlas of Prostatic Cytology: Techniques and Diagnosis
Same group of cells at higher magnification: the condensed chromatin and the local prominence of the nucleoli are now more clearly recognizable. x 630 Fig. 39a. Pap IV atypia: marked variation in nuclear size and increased chromatin density; conspicuous to prominent nucleoli. x 400 Fig. 39b. Same group of cells at higher magnification: some nucleoli display loss of circularity; in parts there is clumping of the chromatin; some nuclei are round to oval in shape. Differential diagnosis: atypical hyperplasia or grade I carcinoma.
X 630 Fig. 39a. Pap IV atypia: marked variation in nuclear size and increased chromatin density; conspicuous to prominent nucleoli. x 400 Fig. 39b. Same group of cells at higher magnification: some nucleoli display loss of circularity; in parts there is clumping of the chromatin; some nuclei are round to oval in shape. Differential diagnosis: atypical hyperplasia or grade I carcinoma. x 630 47 5 Secondary Findings In addition to prostatic epithelial cells, a variety of other cells are found in smears of prostatic aspirates.
35 a. Pap III atypia: disturbed nuclear arrangement, moderately condensed chromatin and conspicuous nucleoli. x 400 44 Fig. 35b. Same case at higher magnification: isolated fine chromatin clumping is now evident, together with low-grade loss of circularity of many nucleoli. x 630 Fig. 36a. Marked varIatIOn in nuclear size and disturbed nuclear arrangement. Conspicuous nucleoli are seen throughout the group. x 400 Fig. 36b. Same case at higher magnification: nucleoli are still only conspicuous, not prominent.
Atlas of Prostatic Cytology: Techniques and Diagnosis by Prof. Dr. Wolfgang Leistenschneider, Prof. Dr. Reinhard Nagel (auth.)